Cervical cancer elimination possible within two
The study will be published online in The Lancet Public Health on February 10.
In 2018, the World Health Organization (WHO) issued a global call to eliminate cervical cancer as a public health problem, setting a disease target of four or fewer cases per 100,000 women. With vaccination against HPV, the virus known to cause cervical cancer, and early detection through screening, cervical cancer is one of the most preventable and treatable forms of cancer.
Cervical cancer screening using Pap testing is recommended every three years for women ages 21-65 years, yet there is a large proportion of women who do not adhere to guidelines, either screening too much or too little; an estimated 14% of women are never screened.
This study is the first known comparative modeling analysis to project a timeframe for cervical cancer elimination in the U.S. The researchers used two independent disease modeling platforms (one from Harvard Chan School and one from Cancer Council New South Wales, Australia) to compare nine different HPV vaccination and cervical cancer screening interventions with a "status quo" scenario reflecting current screening and vaccination practices. They evaluated the potential for each scenario to achieve a threshold for cervical cancer elimination of four cases per 100,000 women, as well as a more ambitious threshold of one case per 100,000 women, over time.标签：