Second wind: New technology to help diagnose and
The technology also has the potential to see whether treatments for respiratory illnesses are working much earlier.
The study was published in Scientific Reports in January 2020.
"Since pulmonary function tests are measured at the mouth, these tests are unable to localise where in the lung any change in function originates. Additionally, CT scans, while providing quality 3-D images, cannot image the lung while it is breathing, which means airflow through the airways and into the lung tissue cannot be measured."
Research by Dr. Murrie and the multi-disciplinary collaboration of physicists, engineers, biologists and clinicians are changing this approach to the diagnosis and treatment of lung diseases, by determining the functional lung movement and airflow in live mice, acquired through X-ray technology at 30 frames per second.
A comparison of a cystic fibrosis mouse model against a healthy control mouse allowed researchers to observe a dramatic reduction in lung aeration in the left lung of the diseased mouse largely due to an obstructed airway path.标签：